United Airlines flight UA 2421: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 09:00 Tulsa (TUL) 10:45 Houston George Bush (IAH) C
UA 2421 Non-stop Airbus A319 (319) 1:45 Effective 2026-03-29 through 2026-04-29
Daily 10:25 Palm Springs (PSP) 13:33 Denver (DEN)
UA 2421 Non-stop Airbus A319 (319) 2:08 Effective 2026-03-05 through 2026-03-28
Daily 10:30 Missoula (MSO) 12:32 Denver (DEN)
UA 2421 Non-stop Boeing 737-800 (738) 2:02 Effective 2026-06-25 through 2026-10-24
Daily 13:25 Denver (DEN) 17:57 Indianapolis (IND)
UA 2421 Non-stop Boeing 737-800 (738) 2:32 Effective 2026-04-30 through 2026-05-20
Daily 13:25 Denver (DEN) 17:57 Indianapolis (IND)
UA 2421 Non-stop Airbus A320 (320) 2:32 Effective 2026-05-21 through 2026-10-24
Mon-Wed,Fri,Sun 13:37 Chicago O'Hare (ORD) 1 16:53 Newark Liberty, New York (EWR) A
UA 2421 Non-stop Airbus A321neo (32Q) 2:16 Valid until 2026-01-05
Sat 13:44 Chicago O'Hare (ORD) 1 16:59 Newark Liberty, New York (EWR) A
UA 2421 Non-stop Airbus A321neo (32Q) 2:15 Operates only on 2026-01-03
Daily 16:20 Denver (DEN) 21:59 Fort Myers (RSW)
UA 2421 Non-stop Boeing 737-800 (738) 3:39 Effective 2026-03-05 through 2026-03-12
Fri-Sun 16:20 Denver (DEN) 21:59 Fort Myers (RSW)
UA 2421 Non-stop Boeing 737-900 (739) 3:39 Effective 2026-03-13 through 2026-03-27
Mon-Thu 16:20 Denver (DEN) 21:59 Fort Myers (RSW)
UA 2421 Non-stop Boeing 737-800 (738) 3:39 Effective 2026-03-16 through 2026-03-26
Sat 16:20 Denver (DEN) 21:59 Fort Myers (RSW)
UA 2421 Non-stop Boeing 737-800 (738) 3:39 Operates only on 2026-03-28
Mon-Fri,Sun 17:50 Indianapolis (IND) 18:10 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Boeing 737 MAX 8 (7M8) 1:20 Effective 2026-01-07 through 2026-02-05
Tue 18:00 Indianapolis (IND) 18:20 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Airbus A319 (319) 1:20 Operates only on 2026-01-06
Sun 18:00 Indianapolis (IND) 18:20 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Airbus A319 (319) 1:20 Operates only on 2026-02-08
Tue,Wed 18:00 Indianapolis (IND) 18:20 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Boeing 737 MAX 8 (7M8) 1:20 Effective 2026-02-10 through 2026-02-11
Sat 18:04 Indianapolis (IND) 18:22 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Airbus A319 (319) 1:18 Effective 2026-02-14 through 2026-02-28
Thu 18:10 Indianapolis (IND) 18:28 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Airbus A319 (319) 1:18 Operates only on 2026-02-12
Tue,Fri 18:10 Indianapolis (IND) 18:28 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Boeing 737-900 (739) 1:18 Effective 2026-02-13 through 2026-02-17
Mon,Thu,Fri,Sun 18:10 Indianapolis (IND) 18:28 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Boeing 737-800 (738) 1:18 Effective 2026-02-15 through 2026-03-02
Wed 18:10 Indianapolis (IND) 18:28 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Boeing 737 MAX 9 (7M9) 1:18 Effective 2026-02-18 through 2026-03-04
Tue 18:10 Indianapolis (IND) 18:28 Chicago O'Hare (ORD) 1
UA 2421 Non-stop Boeing 737-900 (739) 1:18 Effective 2026-02-24 through 2026-03-03
Non-Direct Flights:
Daily 10:25 Palm Springs (PSP) 21:59 Fort Myers (RSW)
UA 2421 1-stop Airbus A319 (319) 8:34 Effective 2026-03-05 through 2026-03-28
Daily 10:30 Missoula (MSO) 17:57 Indianapolis (IND)
UA 2421 1-stop Boeing 737-800 (738) 5:27 Effective 2026-06-25 through 2026-10-24
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This flight number is listed as serving the following routes:
United Airlines flight UA 2421: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

United Airlines UA2421
Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Airbus A319 (319)

Direct Flights:

United Airlines UA2421
Effective 2026-03-05 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Airbus A319 (319)

Direct Flights:

United Airlines UA2421
Effective 2026-06-25 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:02, non-stop
Boeing 737-800 (738)

Direct Flights:

United Airlines UA2421
Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:32, non-stop
Boeing 737-800 (738)

Direct Flights:

United Airlines UA2421
Effective 2026-05-21 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:32, non-stop
Airbus A320 (320)

Direct Flights:

United Airlines UA2421
Valid until 2026-01-05
Mon
Tue
Wed
Thu
-
Fri
Sat
-
Sun
Duration: 2:16, non-stop
Airbus A321neo (32Q)

Direct Flights:

United Airlines UA2421
Operates only on 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:15, non-stop
Airbus A321neo (32Q)

Direct Flights:

United Airlines UA2421
Effective 2026-03-05 through 2026-03-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:39, non-stop
Boeing 737-800 (738)

Direct Flights:

United Airlines UA2421
Effective 2026-03-13 through 2026-03-27
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
Sun
Duration: 3:39, non-stop
Boeing 737-900 (739)

Direct Flights:

United Airlines UA2421
Effective 2026-03-16 through 2026-03-26
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 3:39, non-stop
Boeing 737-800 (738)

Direct Flights:

United Airlines UA2421
Operates only on 2026-03-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 3:39, non-stop
Boeing 737-800 (738)

Direct Flights:

United Airlines UA2421
Effective 2026-01-07 through 2026-02-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:20, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

United Airlines UA2421
Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:20, non-stop
Airbus A319 (319)

Direct Flights:

United Airlines UA2421
Operates only on 2026-02-08
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:20, non-stop
Airbus A319 (319)

Direct Flights:

United Airlines UA2421
Effective 2026-02-10 through 2026-02-11
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:20, non-stop
Boeing 737 MAX 8 (7M8)

Direct Flights:

United Airlines UA2421
Effective 2026-02-14 through 2026-02-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:18, non-stop
Airbus A319 (319)

Direct Flights:

United Airlines UA2421
Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:18, non-stop
Airbus A319 (319)

Direct Flights:

United Airlines UA2421
Effective 2026-02-13 through 2026-02-17
Mon
-
Tue
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:18, non-stop
Boeing 737-900 (739)

Direct Flights:

United Airlines UA2421
Effective 2026-02-15 through 2026-03-02
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:18, non-stop
Boeing 737-800 (738)

Direct Flights:

United Airlines UA2421
Effective 2026-02-18 through 2026-03-04
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:18, non-stop
Boeing 737 MAX 9 (7M9)

Direct Flights:

United Airlines UA2421
Effective 2026-02-24 through 2026-03-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:18, non-stop
Boeing 737-900 (739)

Non-Direct Flights:

United Airlines UA2421
Effective 2026-03-05 through 2026-03-28
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 8:34, 1-stop
Airbus A319 (319)

Non-Direct Flights:

United Airlines UA2421
Effective 2026-06-25 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:27, 1-stop
Boeing 737-800 (738)
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Parallax here
This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Newark Liberty, New York (EWR)
  • Denver (DEN) - Fort Myers (RSW)
  • Denver (DEN) - Indianapolis (IND)
  • Indianapolis (IND) - Chicago O'Hare (ORD)
  • Missoula (MSO) - Denver (DEN)
  • Missoula (MSO) - Indianapolis (IND)
  • Palm Springs (PSP) - Denver (DEN)
  • Palm Springs (PSP) - Fort Myers (RSW)
  • Tulsa (TUL) - Houston George Bush (IAH)