KLM flight KL 5221: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 10:54 Denver (DEN) 15:45 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:51 Valid until 2026-01-04 Codeshare flight, operated by Delta Air Lines.(DL 2781)
Wed 13:12 Denver (DEN) 18:10 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-900 (739) 2:58 Operates only on 2026-02-25 Codeshare flight, operated by Delta Air Lines.(DL 530)
Mon 13:15 Denver (DEN) 18:14 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:59 Operates only on 2026-01-05 Codeshare flight, operated by Delta Air Lines.(DL 2181)
Sat 13:15 Denver (DEN) 18:06 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:51 Operates only on 2026-03-28 Codeshare flight, operated by Delta Air Lines.(DL 530)
Tue,Wed 13:16 Denver (DEN) 18:14 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-900 (739) 2:58 Effective 2026-01-20 through 2026-02-11 Codeshare flight, operated by Delta Air Lines.(DL 2235)
Sat 13:31 Denver (DEN) 18:34 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 3:03 Effective 2026-01-10 through 2026-01-17 Codeshare flight, operated by Delta Air Lines.(DL 2181)
Mon-Fri,Sun 14:42 Denver (DEN) 19:43 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 3:01 Effective 2026-01-06 through 2026-01-18 Codeshare flight, operated by Delta Air Lines.(DL 957)
Daily 14:45 Denver (DEN) 19:46 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 3:01 Effective 2026-02-15 through 2026-02-24 Codeshare flight, operated by Delta Air Lines.(DL 957)
Daily 14:45 Denver (DEN) 19:46 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 3:01 Effective 2026-02-26 through 2026-03-07 Codeshare flight, operated by Delta Air Lines.(DL 957)
Mon,Thu,Fri,Sun 14:59 Denver (DEN) 19:56 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:57 Effective 2026-01-19 through 2026-01-30 Codeshare flight, operated by Delta Air Lines.(DL 957)
Mon,Thu-Sun 14:59 Denver (DEN) 19:56 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:57 Effective 2026-01-31 through 2026-02-14 Codeshare flight, operated by Delta Air Lines.(DL 957)
Daily 15:05 Denver (DEN) 20:02 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:57 Effective 2026-03-08 through 2026-03-27 Codeshare flight, operated by Delta Air Lines.(DL 957)
Sat 15:24 Denver (DEN) 20:20 Atlanta (ATL) S KL 5221 Non-stop Airbus A321 (321) 2:56 Operates only on 2026-01-24 Codeshare flight, operated by Delta Air Lines.(DL 957)
Daily 16:00 Knoxville (TYS) 17:07 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-900 (739) 1:07 Effective from 2026-10-25 Codeshare flight, operated by Delta Air Lines.(DL 1148)
Mon,Thu,Fri,Sun 17:45 Atlanta (ATL) S 17:50 Panama City (ECP) KL 5221 Non-stop Boeing 737-800 (738) 1:05 Effective 2026-04-13 through 2026-05-22 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon,Thu,Fri,Sun 17:45 Atlanta (ATL) S 17:50 Panama City (ECP) KL 5221 Non-stop Boeing 737-800 (738) 1:05 Effective 2026-05-25 through 2026-06-08 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 17:45 Atlanta (ATL) S 17:50 Panama City (ECP) KL 5221 Non-stop Boeing 737-800 (738) 1:05 Effective 2026-06-09 through 2026-07-06 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 17:45 Atlanta (ATL) S 17:51 Panama City (ECP) KL 5221 Non-stop Boeing 737-800 (738) 1:06 Effective 2026-07-07 through 2026-09-04 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 17:45 Atlanta (ATL) S 17:51 Panama City (ECP) KL 5221 Non-stop Boeing 737-800 (738) 1:06 Effective 2026-09-07 through 2026-10-05 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 17:45 Atlanta (ATL) S 17:50 Panama City (ECP) KL 5221 Non-stop Boeing 737-800 (738) 1:05 Effective 2026-10-06 through 2026-10-23 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 17:53 Atlanta (ATL) S 17:58 Panama City (ECP) KL 5221 Non-stop Boeing 717 (717) 1:05 Effective 2026-03-29 through 2026-04-12 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Sat 17:53 Atlanta (ATL) S 17:57 Panama City (ECP) KL 5221 Non-stop Boeing 717 (717) 1:04 Effective 2026-04-04 through 2026-04-11 Codeshare flight, operated by Delta Air Lines.(DL 1604)
Mon,Thu,Fri,Sun 18:45 Panama City (ECP) 21:08 Atlanta (ATL) S KL 5221 Non-stop Boeing 717 (717) 1:23 Effective 2026-03-29 through 2026-04-12 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon,Thu,Fri,Sun 19:05 Panama City (ECP) 21:22 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-800 (738) 1:17 Effective 2026-04-13 through 2026-05-22 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon,Thu,Fri,Sun 19:05 Panama City (ECP) 21:22 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-800 (738) 1:17 Effective 2026-05-25 through 2026-06-08 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 19:05 Panama City (ECP) 21:22 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-800 (738) 1:17 Effective 2026-06-09 through 2026-07-06 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 19:05 Panama City (ECP) 21:21 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-800 (738) 1:16 Effective 2026-07-07 through 2026-09-04 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 19:05 Panama City (ECP) 21:21 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-800 (738) 1:16 Effective 2026-09-07 through 2026-10-05 Codeshare flight, operated by Delta Air Lines.(DL 3053)
Mon-Fri,Sun 19:05 Panama City (ECP) 21:23 Atlanta (ATL) S KL 5221 Non-stop Boeing 737-800 (738) 1:18 Effective 2026-10-06 through 2026-10-23 Codeshare flight, operated by Delta Air Lines.(DL 3053)

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This flight number is listed as serving the following routes:

Atlanta (ATL) - Panama City (ECP)
Denver (DEN) - Atlanta (ATL)
Knoxville (TYS) - Atlanta (ATL)

All KLM flights

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KLM flight KL 5221: Multiple routes

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FLIGHT SCHEDULE

Direct Codeshare Flights:

KLM KL5221

10:54

Denver (DEN)

15:45

Atlanta (ATL) S

Valid until 2026-01-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by Delta Air Lines. (DL 2781)

Duration: 2:51, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

13:12

Denver (DEN)

18:10

Atlanta (ATL) S

Operates only on 2026-02-25

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 530)

Duration: 2:58, non-stop
Boeing 737-900 (739)

Direct Codeshare Flights:

KLM KL5221

13:15

Denver (DEN)

18:14

Atlanta (ATL) S

Operates only on 2026-01-05

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 2181)

Duration: 2:59, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

13:15

Denver (DEN)

18:06

Atlanta (ATL) S

Operates only on 2026-03-28

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 530)

Duration: 2:51, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

13:16

Denver (DEN)

18:14

Atlanta (ATL) S

Effective 2026-01-20 through 2026-02-11

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 2235)

Duration: 2:58, non-stop
Boeing 737-900 (739)

Direct Codeshare Flights:

KLM KL5221

13:31

Denver (DEN)

18:34

Atlanta (ATL) S

Effective 2026-01-10 through 2026-01-17

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 2181)

Duration: 3:03, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

14:42

Denver (DEN)

19:43

Atlanta (ATL) S

Effective 2026-01-06 through 2026-01-18

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 3:01, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

14:45

Denver (DEN)

19:46

Atlanta (ATL) S

Effective 2026-02-15 through 2026-02-24

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 3:01, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

14:45

Denver (DEN)

19:46

Atlanta (ATL) S

Effective 2026-02-26 through 2026-03-07

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 3:01, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

14:59

Denver (DEN)

19:56

Atlanta (ATL) S

Effective 2026-01-19 through 2026-01-30

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 2:57, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

14:59

Denver (DEN)

19:56

Atlanta (ATL) S

Effective 2026-01-31 through 2026-02-14

Mon

Tue
-

Wed
-

Thu

Fri

Sat

Sun

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 2:57, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

15:05

Denver (DEN)

20:02

Atlanta (ATL) S

Effective 2026-03-08 through 2026-03-27

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 2:57, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

15:24

Denver (DEN)

20:20

Atlanta (ATL) S

Operates only on 2026-01-24

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 957)

Duration: 2:56, non-stop
Airbus A321 (321)

Direct Codeshare Flights:

KLM KL5221

16:00

Knoxville (TYS)

17:07

Atlanta (ATL) S

Effective from 2026-10-25

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by Delta Air Lines. (DL 1148)

Duration: 1:07, non-stop
Boeing 737-900 (739)

Direct Codeshare Flights:

KLM KL5221

17:45

Atlanta (ATL) S

17:50

Panama City (ECP)

Effective 2026-04-13 through 2026-05-22

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:05, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

17:45

Atlanta (ATL) S

17:50

Panama City (ECP)

Effective 2026-05-25 through 2026-06-08

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:05, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

17:45

Atlanta (ATL) S

17:50

Panama City (ECP)

Effective 2026-06-09 through 2026-07-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:05, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

17:45

Atlanta (ATL) S

17:51

Panama City (ECP)

Effective 2026-07-07 through 2026-09-04

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:06, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

17:45

Atlanta (ATL) S

17:51

Panama City (ECP)

Effective 2026-09-07 through 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:06, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

17:45

Atlanta (ATL) S

17:50

Panama City (ECP)

Effective 2026-10-06 through 2026-10-23

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:05, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

17:53

Atlanta (ATL) S

17:58

Panama City (ECP)

Effective 2026-03-29 through 2026-04-12

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:05, non-stop
Boeing 717 (717)

Direct Codeshare Flights:

KLM KL5221

17:53

Atlanta (ATL) S

17:57

Panama City (ECP)

Effective 2026-04-04 through 2026-04-11

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by Delta Air Lines. (DL 1604)

Duration: 1:04, non-stop
Boeing 717 (717)

Direct Codeshare Flights:

KLM KL5221

18:45

Panama City (ECP)

21:08

Atlanta (ATL) S

Effective 2026-03-29 through 2026-04-12

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:23, non-stop
Boeing 717 (717)

Direct Codeshare Flights:

KLM KL5221

19:05

Panama City (ECP)

21:22

Atlanta (ATL) S

Effective 2026-04-13 through 2026-05-22

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:17, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

19:05

Panama City (ECP)

21:22

Atlanta (ATL) S

Effective 2026-05-25 through 2026-06-08

Mon

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:17, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

19:05

Panama City (ECP)

21:22

Atlanta (ATL) S

Effective 2026-06-09 through 2026-07-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:17, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

19:05

Panama City (ECP)

21:21

Atlanta (ATL) S

Effective 2026-07-07 through 2026-09-04

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:16, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

19:05

Panama City (ECP)

21:21

Atlanta (ATL) S

Effective 2026-09-07 through 2026-10-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:16, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

KLM KL5221

19:05

Panama City (ECP)

21:23

Atlanta (ATL) S

Effective 2026-10-06 through 2026-10-23

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by Delta Air Lines. (DL 3053)

Duration: 1:18, non-stop
Boeing 737-800 (738)

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This flight number is listed as serving the following routes:

Atlanta (ATL) - Panama City (ECP)
Denver (DEN) - Atlanta (ATL)
Knoxville (TYS) - Atlanta (ATL)

All KLM flights

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- CACHE: False - LANG: en - IS_EU: False