Delta Air Lines flight DL 5621: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Thu,Fri 08:55 New York John F. Kennedy (JFK) 4 12:09 Sarasota/Bradenton (SRQ)
DL 5621 Non-stop Embraer EMB 175 (E75) 3:14 Effective 2026-01-08 through 2026-01-09
Sat 09:28 New York John F. Kennedy (JFK) 4 12:43 Sarasota/Bradenton (SRQ)
DL 5621 Non-stop Embraer EMB 175 (E75) 3:15 Operates only on 2026-01-10
Sun 09:30 New York LaGuardia (LGA) C 11:09 Nashville (BNA)
DL 5621 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:39 Effective 2026-03-08 through 2026-04-12
Wed,Thu 09:45 New York LaGuardia (LGA) C 12:22 Louisville (SDF)
DL 5621 Non-stop Embraer EMB 175 (E75) 2:37 Valid until 2026-01-01
Mon,Tue,Fri-Sun 09:56 New York LaGuardia (LGA) C 12:33 Louisville (SDF)
DL 5621 Non-stop Embraer EMB 175 (E75) 2:37 Valid until 2026-01-04
Mon-Fri 10:35 New York LaGuardia (LGA) C 12:14 Nashville (BNA)
DL 5621 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:39 Effective 2026-03-09 through 2026-04-10
Mon-Fri 12:05 Chicago O'Hare (ORD) 5 15:27 New York LaGuardia (LGA) C
DL 5621 Non-stop Embraer EMB 175 (E75) 2:22 Effective 2026-02-12 through 2026-03-06
Sun 12:30 Nashville (BNA) 15:52 New York LaGuardia (LGA) C
DL 5621 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:22 Effective 2026-03-08 through 2026-04-12
Sat 12:30 Nashville (BNA) 15:52 New York LaGuardia (LGA) C
DL 5621 Non-stop Embraer EMB 175 (E75) 2:22 Effective 2026-03-14 through 2026-04-11
Thu,Fri 12:49 Sarasota/Bradenton (SRQ) 15:46 New York John F. Kennedy (JFK) 4
DL 5621 Non-stop Embraer EMB 175 (E75) 2:57 Effective 2026-01-08 through 2026-01-09
Sat 13:23 Sarasota/Bradenton (SRQ) 16:14 New York John F. Kennedy (JFK) 4
DL 5621 Non-stop Embraer EMB 175 (E75) 2:51 Operates only on 2026-01-10
Mon-Fri 13:37 Nashville (BNA) 17:00 New York LaGuardia (LGA) C
DL 5621 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:23 Effective 2026-03-09 through 2026-04-10
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This flight number is listed as serving the following routes:


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Delta Air Lines flight DL 5621: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Delta Air Lines DL5621
08:55
New York John F. Kennedy (JFK) 4

12:09
Sarasota/Bradenton (SRQ)
Effective 2026-01-08 through 2026-01-09
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 3:14, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
09:28
New York John F. Kennedy (JFK) 4

12:43
Sarasota/Bradenton (SRQ)
Operates only on 2026-01-10
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 3:15, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
09:30
New York LaGuardia (LGA) C

11:09
Nashville (BNA)
Effective 2026-03-08 through 2026-04-12
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:39, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
Delta Air Lines DL5621
09:45
New York LaGuardia (LGA) C

12:22
Louisville (SDF)
Valid until 2026-01-01
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
09:56
New York LaGuardia (LGA) C

12:33
Louisville (SDF)
Valid until 2026-01-04
Mon
Tue
Wed
-
Thu
-
Fri
Sat
Sun
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
10:35
New York LaGuardia (LGA) C

12:14
Nashville (BNA)
Effective 2026-03-09 through 2026-04-10
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:39, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
Delta Air Lines DL5621
12:05
Chicago O'Hare (ORD) 5

15:27
New York LaGuardia (LGA) C
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:22, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
12:30
Nashville (BNA)

15:52
New York LaGuardia (LGA) C
Effective 2026-03-08 through 2026-04-12
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:22, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
Delta Air Lines DL5621
12:30
Nashville (BNA)

15:52
New York LaGuardia (LGA) C
Effective 2026-03-14 through 2026-04-11
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:22, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
12:49
Sarasota/Bradenton (SRQ)

15:46
New York John F. Kennedy (JFK) 4
Effective 2026-01-08 through 2026-01-09
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 2:57, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
13:23
Sarasota/Bradenton (SRQ)

16:14
New York John F. Kennedy (JFK) 4
Operates only on 2026-01-10
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:51, non-stop
Embraer EMB 175 (E75)
Direct Flights:
Delta Air Lines DL5621
13:37
Nashville (BNA)

17:00
New York LaGuardia (LGA) C
Effective 2026-03-09 through 2026-04-10
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:23, non-stop
Embraer EMB 170 / EMB 175 (E70)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - New York LaGuardia (LGA)
  • Nashville (BNA) - New York LaGuardia (LGA)
  • New York John F. Kennedy (JFK) - Sarasota/Bradenton (SRQ)
  • New York LaGuardia (LGA) - Louisville (SDF)
All Delta Air Lines flights
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