Delta Air Lines flight DL 5353: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Sat 13:00 Cincinnati (CVG) 14:15 Detroit (DTW) M
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:15 Effective 2026-03-14 through 2026-04-11
Tue 13:33 New York LaGuardia (LGA) C 15:11 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:38 Operates only on 2026-02-03
Fri 13:45 New York LaGuardia (LGA) C 15:23 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:38 Effective 2026-01-23 through 2026-01-30
Sun 13:45 New York LaGuardia (LGA) C 15:21 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:36 Effective 2026-02-15 through 2026-03-01
Mon-Fri,Sun 13:50 New York LaGuardia (LGA) C 15:28 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:38 Effective 2026-01-05 through 2026-01-22
Mon-Thu,Sun 13:50 New York LaGuardia (LGA) C 15:28 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:38 Effective 2026-01-25 through 2026-02-02
Mon-Fri,Sun 13:50 New York LaGuardia (LGA) C 15:28 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:38 Effective 2026-02-04 through 2026-02-11
Mon-Fri 13:59 New York LaGuardia (LGA) C 15:35 Pittsburgh (PIT)
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:36 Effective 2026-02-12 through 2026-03-06
Sun 16:05 Pittsburgh (PIT) 17:37 New York LaGuardia (LGA) C
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:32 Effective 2026-02-15 through 2026-03-01
Mon-Fri 16:17 Pittsburgh (PIT) 17:49 New York LaGuardia (LGA) C
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:32 Effective 2026-02-12 through 2026-03-06
Mon-Fri,Sun 19:42 Cleveland (CLE) 20:45 Detroit (DTW) M
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:03 Effective from 2026-10-06
Mon-Fri,Sun 19:45 Cleveland (CLE) 20:45 Detroit (DTW) M
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-04-13 through 2026-05-22
Mon-Fri,Sun 19:45 Cleveland (CLE) 20:45 Detroit (DTW) M
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-05-25 through 2026-09-04
Mon-Fri,Sun 19:45 Cleveland (CLE) 20:45 Detroit (DTW) M
DL 5353 Non-stop Canadair CRJ 900 (CR9) 1:00 Effective 2026-09-07 through 2026-10-05
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This flight number is listed as serving the following routes:


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Delta Air Lines flight DL 5353: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Delta Air Lines DL5353
13:00
Cincinnati (CVG)

14:15
Detroit (DTW) M
Effective 2026-03-14 through 2026-04-11
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:15, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:33
New York LaGuardia (LGA) C

15:11
Pittsburgh (PIT)
Operates only on 2026-02-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:38, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:45
New York LaGuardia (LGA) C

15:23
Pittsburgh (PIT)
Effective 2026-01-23 through 2026-01-30
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:38, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:45
New York LaGuardia (LGA) C

15:21
Pittsburgh (PIT)
Effective 2026-02-15 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:36, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:50
New York LaGuardia (LGA) C

15:28
Pittsburgh (PIT)
Effective 2026-01-05 through 2026-01-22
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:38, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:50
New York LaGuardia (LGA) C

15:28
Pittsburgh (PIT)
Effective 2026-01-25 through 2026-02-02
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 1:38, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:50
New York LaGuardia (LGA) C

15:28
Pittsburgh (PIT)
Effective 2026-02-04 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:38, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
13:59
New York LaGuardia (LGA) C

15:35
Pittsburgh (PIT)
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:36, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
16:05
Pittsburgh (PIT)

17:37
New York LaGuardia (LGA) C
Effective 2026-02-15 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:32, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
16:17
Pittsburgh (PIT)

17:49
New York LaGuardia (LGA) C
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:32, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
19:42
Cleveland (CLE)

20:45
Detroit (DTW) M
Effective from 2026-10-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:03, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
19:45
Cleveland (CLE)

20:45
Detroit (DTW) M
Effective 2026-04-13 through 2026-05-22
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
19:45
Cleveland (CLE)

20:45
Detroit (DTW) M
Effective 2026-05-25 through 2026-09-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
Delta Air Lines DL5353
19:45
Cleveland (CLE)

20:45
Detroit (DTW) M
Effective 2026-09-07 through 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:00, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Cincinnati (CVG) - Detroit (DTW)
  • Cleveland (CLE) - Detroit (DTW)
  • Pittsburgh (PIT) - New York LaGuardia (LGA)
All Delta Air Lines flights
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