American Airlines flight AA 5280: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 06:00 Kansas City (MCI) 09:45 Philadelphia (PHL) F
AA 5280 Non-stop Canadair CRJ 700 (CR7) 2:45 Valid until 2026-01-05
Daily 08:35 Dallas Fort Worth (DFW) E 09:38 Lawton/Fort Sill (LAW)
AA 5280 Non-stop Canadair CRJ 700 (CR7) 1:03 Effective 2026-08-05 through 2026-09-08
Daily 09:00 Charlotte (CLT) 11:04 Wilkes-Barre/Scranton (AVP)
AA 5280 Non-stop Canadair CRJ 900 (CR9) 2:04 Effective 2026-09-09 through 2026-10-04
Mon-Fri 10:00 Dayton (DAY) 11:34 Ronald Reagan Washington (DCA) 2
AA 5280 Non-stop Canadair CRJ 700 (CR7) 1:34 Effective 2026-01-07 through 2026-02-11
Daily 10:20 Lawton/Fort Sill (LAW) 11:18 Dallas Fort Worth (DFW) E
AA 5280 Non-stop Canadair CRJ 700 (CR7) 0:58 Effective 2026-08-05 through 2026-09-08
Daily 11:30 Ronald Reagan Washington (DCA) 2 13:02 Manchester (MHT)
AA 5280 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-07-02 through 2026-08-04
Daily 11:59 Wilkes-Barre/Scranton (AVP) 13:55 Charlotte (CLT)
AA 5280 Non-stop Canadair CRJ 900 (CR9) 1:56 Effective 2026-09-09 through 2026-10-04
Daily 13:05 Charlotte (CLT) 13:58 Memphis (MEM)
AA 5280 Non-stop Canadair CRJ 900 (CR9) 1:53 Effective 2026-05-21 through 2026-07-01
Daily 13:32 Manchester (MHT) 15:19 Ronald Reagan Washington (DCA) 2
AA 5280 Non-stop Canadair CRJ 700 (CR7) 1:47 Effective 2026-07-02 through 2026-08-04
Daily 14:33 Memphis (MEM) 17:25 Charlotte (CLT)
AA 5280 Non-stop Canadair CRJ 900 (CR9) 1:52 Effective 2026-05-21 through 2026-07-01
Daily 14:54 Ronald Reagan Washington (DCA) 2 16:14 Wilmington (ILM)
AA 5280 Non-stop Canadair CRJ 700 (CR7) 1:20 Effective 2026-04-07 through 2026-05-20
Daily 15:35 Philadelphia (PHL) F 16:51 Pittsburgh (PIT)
AA 5280 Non-stop Canadair CRJ 900 (CR9) 1:16 Effective from 2026-10-05
Daily 16:36 Philadelphia (PHL) F 18:19 Cleveland (CLE)
AA 5280 Non-stop Canadair CRJ 900 (CR9) 1:43 Effective 2026-03-08 through 2026-04-06
Daily 16:54 Wilmington (ILM) 18:23 Ronald Reagan Washington (DCA) 2
AA 5280 Non-stop Canadair CRJ 700 (CR7) 1:29 Effective 2026-04-07 through 2026-05-20
Daily 18:49 Cleveland (CLE) 20:21 Philadelphia (PHL) F
AA 5280 Non-stop Canadair CRJ 900 (CR9) 1:32 Effective 2026-03-08 through 2026-04-06
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This flight number is listed as serving the following routes:


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American Airlines flight AA 5280: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5280
06:00
Kansas City (MCI)

09:45
Philadelphia (PHL) F
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:45, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
08:35
Dallas Fort Worth (DFW) E

09:38
Lawton/Fort Sill (LAW)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:03, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
09:00
Charlotte (CLT)

11:04
Wilkes-Barre/Scranton (AVP)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5280
10:00
Dayton (DAY)

11:34
Ronald Reagan Washington (DCA) 2
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:34, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
10:20
Lawton/Fort Sill (LAW)

11:18
Dallas Fort Worth (DFW) E
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:58, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
11:30
Ronald Reagan Washington (DCA) 2

13:02
Manchester (MHT)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
11:59
Wilkes-Barre/Scranton (AVP)

13:55
Charlotte (CLT)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5280
13:05
Charlotte (CLT)

13:58
Memphis (MEM)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5280
13:32
Manchester (MHT)

15:19
Ronald Reagan Washington (DCA) 2
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
14:33
Memphis (MEM)

17:25
Charlotte (CLT)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:52, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5280
14:54
Ronald Reagan Washington (DCA) 2

16:14
Wilmington (ILM)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:20, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
15:35
Philadelphia (PHL) F

16:51
Pittsburgh (PIT)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:16, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5280
16:36
Philadelphia (PHL) F

18:19
Cleveland (CLE)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5280
16:54
Wilmington (ILM)

18:23
Ronald Reagan Washington (DCA) 2
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:29, non-stop
Canadair CRJ 700 (CR7)
Direct Flights:
American Airlines AA5280
18:49
Cleveland (CLE)

20:21
Philadelphia (PHL) F
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:32, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Charlotte (CLT) - Memphis (MEM)
  • Charlotte (CLT) - Wilkes-Barre/Scranton (AVP)
  • Cleveland (CLE) - Philadelphia (PHL)
  • Dayton (DAY) - Ronald Reagan Washington (DCA)
  • Kansas City (MCI) - Philadelphia (PHL)
  • Lawton/Fort Sill (LAW) - Dallas Fort Worth (DFW)
  • Philadelphia (PHL) - Pittsburgh (PIT)
  • Ronald Reagan Washington (DCA) - Manchester (MHT)
  • Wilmington (ILM) - Ronald Reagan Washington (DCA)
All American Airlines flights
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