American Airlines flight AA 4395: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 13:00 Boston Logan (BOS) B 15:17 John Glenn Columbus (CMH)
AA 4395 Non-stop Embraer EMB 175 (E75) 2:17 Effective from 2026-10-05
Sat 15:11 New York LaGuardia (LGA) B 16:37 Burlington (BTV)
AA 4395 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-02-14 through 2026-03-07
Sat 15:50 New York LaGuardia (LGA) B 17:15 Burlington (BTV)
AA 4395 Non-stop Embraer EMB 175 (E75) 1:25 Effective 2026-01-10 through 2026-02-07
Daily 16:45 New York LaGuardia (LGA) B 18:44 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 2:59 Effective 2026-04-07 through 2026-05-20
Daily 17:15 New York LaGuardia (LGA) B 19:18 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:03 Effective 2026-05-21 through 2026-07-01
Daily 17:15 New York LaGuardia (LGA) B 19:23 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:08 Effective 2026-07-02 through 2026-08-04
Daily 17:15 New York LaGuardia (LGA) B 19:19 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:04 Effective 2026-08-05 through 2026-09-08
Mon-Thu,Sun 17:40 New York LaGuardia (LGA) B 19:58 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:18 Effective 2026-01-06 through 2026-02-11
Mon-Thu,Sun 17:40 New York LaGuardia (LGA) B 20:06 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:26 Effective 2026-02-12 through 2026-03-05
Mon-Thu,Sun 17:40 New York LaGuardia (LGA) B 19:57 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:17 Effective 2026-03-08 through 2026-04-06
Fri 17:45 New York LaGuardia (LGA) B 19:05 Burlington (BTV)
AA 4395 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:20 Valid until 2026-01-02
Fri 17:45 New York LaGuardia (LGA) B 19:10 Burlington (BTV)
AA 4395 Non-stop Embraer EMB 175 (E75) 1:25 Effective 2026-01-09 through 2026-02-06
Fri 17:45 New York LaGuardia (LGA) B 19:11 Burlington (BTV)
AA 4395 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-02-13 through 2026-03-06
Fri 17:45 New York LaGuardia (LGA) B 19:09 Burlington (BTV)
AA 4395 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2026-03-13 through 2026-04-03
Daily 20:15 New York LaGuardia (LGA) B 22:27 Des Moines (DSM)
AA 4395 Non-stop Embraer EMB 175 (E75) 3:12 Effective 2026-09-09 through 2026-10-04
Mon 20:45 Chicago O'Hare (ORD) 3 00:06 Richmond (RIC)
AA 4395 Non-stop Embraer EMB 175 (E75) 2:21 Operates only on 2026-01-05
The flight arrives 1 day after departure.
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4395: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4395
13:00
Boston Logan (BOS) B

15:17
John Glenn Columbus (CMH)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
15:11
New York LaGuardia (LGA) B

16:37
Burlington (BTV)
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
15:50
New York LaGuardia (LGA) B

17:15
Burlington (BTV)
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:25, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
16:45
New York LaGuardia (LGA) B

18:44
Des Moines (DSM)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:59, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:15
New York LaGuardia (LGA) B

19:18
Des Moines (DSM)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:03, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:15
New York LaGuardia (LGA) B

19:23
Des Moines (DSM)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:08, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:15
New York LaGuardia (LGA) B

19:19
Des Moines (DSM)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:04, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:40
New York LaGuardia (LGA) B

19:58
Des Moines (DSM)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 3:18, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:40
New York LaGuardia (LGA) B

20:06
Des Moines (DSM)
Effective 2026-02-12 through 2026-03-05
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 3:26, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:40
New York LaGuardia (LGA) B

19:57
Des Moines (DSM)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 3:17, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:45
New York LaGuardia (LGA) B

19:05
Burlington (BTV)
Valid until 2026-01-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:20, non-stop
Embraer EMB 170 / EMB 175 (E70)
Direct Flights:
American Airlines AA4395
17:45
New York LaGuardia (LGA) B

19:10
Burlington (BTV)
Effective 2026-01-09 through 2026-02-06
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:25, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:45
New York LaGuardia (LGA) B

19:11
Burlington (BTV)
Effective 2026-02-13 through 2026-03-06
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
17:45
New York LaGuardia (LGA) B

19:09
Burlington (BTV)
Effective 2026-03-13 through 2026-04-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:24, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
20:15
New York LaGuardia (LGA) B

22:27
Des Moines (DSM)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:12, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4395
20:45
Chicago O'Hare (ORD) 3

00:06(+1)
Richmond (RIC)
Operates only on 2026-01-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:21, non-stop
Embraer EMB 175 (E75)
The flight arrives 1 day after departure.
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This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - John Glenn Columbus (CMH)
  • Chicago O'Hare (ORD) - Richmond (RIC)
  • New York LaGuardia (LGA) - Burlington (BTV)
  • New York LaGuardia (LGA) - Des Moines (DSM)
All American Airlines flights
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