Alaska Airlines flight AS 6645: Multiple routes

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Daily 07:00 Dallas Fort Worth (DFW) 08:37 McAllen/Mission (MFE)
AS 6645 Non-stop Airbus A319 (319) 1:37 Effective 2026-05-21 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 2125)
Daily 08:08 Dallas Fort Worth (DFW) 09:32 Amarillo (AMA)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2026-04-07 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 3441)
Daily 09:56 McAllen/Mission (MFE) 11:39 Dallas Fort Worth (DFW)
AS 6645 Non-stop Airbus A319 (319) 1:43 Effective 2026-05-21 through 2026-07-01
Codeshare flight, operated by American Airlines.(AA 2125)
Daily 09:58 McAllen/Mission (MFE) 11:39 Dallas Fort Worth (DFW)
AS 6645 Non-stop Airbus A319 (319) 1:41 Effective 2026-07-02 through 2026-08-04
Codeshare flight, operated by American Airlines.(AA 2131)
Daily 10:27 Amarillo (AMA) 11:39 Dallas Fort Worth (DFW)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:12 Effective 2026-05-13 through 2026-05-20
Codeshare flight, operated by American Airlines.(AA 3441)
Mon-Fri,Sun 17:59 Chicago O'Hare (ORD) 3 22:03 Fort Myers (RSW)
AS 6645 Non-stop Boeing 737-800 (738) 3:04 Effective 2026-01-06 through 2026-02-04
Codeshare flight, operated by American Airlines.(AA 391)
Mon-Wed,Sun 17:59 Chicago O'Hare (ORD) 3 22:03 Fort Myers (RSW)
AS 6645 Non-stop Boeing 737-800 (738) 3:04 Effective 2026-02-08 through 2026-02-11
Codeshare flight, operated by American Airlines.(AA 391)
Sat 18:05 Chicago O'Hare (ORD) 3 22:08 Fort Myers (RSW)
AS 6645 Non-stop Boeing 737-800 (738) 3:03 Effective 2026-01-10 through 2026-02-07
Codeshare flight, operated by American Airlines.(AA 391)
Thu,Fri 18:14 Chicago O'Hare (ORD) 3 22:17 Fort Myers (RSW)
AS 6645 Non-stop Boeing 737-800 (738) 3:03 Effective 2026-02-05 through 2026-02-06
Codeshare flight, operated by American Airlines.(AA 391)
Daily 18:50 Dallas Fort Worth (DFW) 20:03 Amarillo (AMA)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:13 Effective 2026-09-09 through 2026-10-01
Codeshare flight, operated by American Airlines.(AA 3788)
Sat,Sun 18:50 Dallas Fort Worth (DFW) 20:01 Houston Hobby (HOU)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:11 Effective 2026-10-03 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 3441)
Daily 18:50 Dallas Fort Worth (DFW) 20:04 Amarillo (AMA)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:14 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 3607)
Tue 19:45 Dallas Fort Worth (DFW) E 21:17 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-03-10 through 2026-03-17
Codeshare flight, operated by American Airlines.(AA 6185)
Daily 19:49 Chicago O'Hare (ORD) 3 23:57 Fort Myers (RSW)
AS 6645 Non-stop Boeing 737-800 (738) 3:08 Valid until 2026-01-05
Codeshare flight, operated by American Airlines.(AA 648)
Mon,Wed-Fri,Sun 19:52 Dallas Fort Worth (DFW) E 21:24 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-03-08 through 2026-03-20
Codeshare flight, operated by American Airlines.(AA 6185)
Mon,Wed-Sun 19:52 Dallas Fort Worth (DFW) E 21:24 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:32 Effective 2026-03-21 through 2026-04-06
Codeshare flight, operated by American Airlines.(AA 6185)
Mon,Wed,Fri 19:55 Dallas Fort Worth (DFW) E 21:23 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:28 Effective 2026-02-18 through 2026-02-25
Codeshare flight, operated by American Airlines.(AA 6185)
Mon,Wed 19:55 Dallas Fort Worth (DFW) E 21:23 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:28 Effective 2026-03-02 through 2026-03-04
Codeshare flight, operated by American Airlines.(AA 6185)
Mon,Tue,Thu,Fri,Sun 19:59 Dallas Fort Worth (DFW) E 21:27 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:28 Effective 2026-02-12 through 2026-02-19
Codeshare flight, operated by American Airlines.(AA 6185)
Tue,Thu,Fri,Sun 19:59 Dallas Fort Worth (DFW) E 21:27 Amarillo (AMA)
AS 6645 Non-stop Canadair CRJ 700 (CR7) 1:28 Effective 2026-02-22 through 2026-03-06
Codeshare flight, operated by American Airlines.(AA 6185)
Daily 20:24 Amarillo (AMA) 21:50 Dallas Fort Worth (DFW)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:26 Effective from 2026-10-05
Codeshare flight, operated by American Airlines.(AA 3607)
Daily 20:34 Amarillo (AMA) 21:50 Dallas Fort Worth (DFW)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:16 Effective 2026-09-09 through 2026-10-01
Codeshare flight, operated by American Airlines.(AA 3788)
Sat,Sun 20:35 Houston Hobby (HOU) 21:50 Dallas Fort Worth (DFW)
AS 6645 Non-stop Embraer EMB 175 (E75) 1:15 Effective 2026-10-03 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 3441)
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This flight number is listed as serving the following routes:
Alaska Airlines flight AS 6645: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-05-21 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 2125)
Duration: 1:37, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3441)
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 2125)
Duration: 1:43, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 2131)
Duration: 1:41, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-05-13 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3441)
Duration: 1:12, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-01-06 through 2026-02-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 391)
Duration: 3:04, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-02-08 through 2026-02-11
Mon
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 391)
Duration: 3:04, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-01-10 through 2026-02-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by American Airlines. (AA 391)
Duration: 3:03, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-02-05 through 2026-02-06
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 391)
Duration: 3:03, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-09-09 through 2026-10-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3788)
Duration: 1:13, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-10-03 through 2026-10-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3441)
Duration: 1:11, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3607)
Duration: 1:14, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-03-10 through 2026-03-17
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 648)
Duration: 3:08, non-stop
Boeing 737-800 (738)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-03-08 through 2026-03-20
Mon
Tue
-
Wed
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-03-21 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:32, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-02-18 through 2026-02-25
Mon
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:28, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-03-02 through 2026-03-04
Mon
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:28, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-02-12 through 2026-02-19
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:28, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-02-22 through 2026-03-06
Mon
-
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Codeshare flight, operated by American Airlines. (AA 6185)
Duration: 1:28, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3607)
Duration: 1:26, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-09-09 through 2026-10-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3788)
Duration: 1:16, non-stop
Embraer EMB 175 (E75)

Direct Codeshare Flights:

Alaska Airlines AS6645
Effective 2026-10-03 through 2026-10-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 3441)
Duration: 1:15, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Fort Myers (RSW)
  • Dallas Fort Worth (DFW) - Amarillo (AMA)
  • Dallas Fort Worth (DFW) - Houston Hobby (HOU)
  • Dallas Fort Worth (DFW) - McAllen/Mission (MFE)